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Hair loss is a pervasive concern affecting millions worldwide, and professionals from different industries have been exploring solutions to counter this challenge. Recent research, "Adult Stem Cell Released Molecules Combined with Microneedling: A Safe and Effective Treatment for Alopecia" by Michael Ryan, MIT, IAT, Psy, D, and Greg Maguire, Ph.D., sheds light on adult donated stem cells as an alternative treatment for alopecia.
Here are the main highlights from the research.
Understanding Hair Loss.
The paper delves into multiple factors that contribute to hair loss. Aging, heredity, hormones, environmental exposure, stress, medications, and nutrition can trigger alopecia. Drawing parallels between hair growth and general stem cell functions, the study emphasizes the pivotal role of the dermal papilla (DP) and the complex interplay between various cells within the hair follicle.
You are probably wondering what the dermal papilla is.
Think of the dermal papilla as the brain of the hair follicle. The dermal papilla is a small, protruding structure at the base of a hair follicle that plays a crucial role in regulating hair growth and development. It is rich in blood vessels and connects to the body's circulatory system, providing nutrients and oxygen to hair follicle cells.
2. The Role of Adult Stem Cells.
The research focuses on the potential of adult stem cells, particularly adipose-derived mesenchymal stem cells (ADSCs), in regrowing hair.
(ADSCs) and fibroblasts contain various proteins and molecules that play essential roles in hair growth. These include PDGF, FGFs, HGF, VEGF, IGF-binding protein precursors, and fibronectin.
Moreover, mesenchymal stem cells aid in clearing out dying cells in hair follicles, reducing inflammation. This process releases a molecule called PGE2, further decreasing inflammation and supporting hair growth.
Stem cells usually release substances that keep their environment healthy. ADSCs might help maintain this environment, preventing stem cells from moving away and supporting hair growth.
During the hair growth and rest cycle, stem cells in hair follicles constantly balance factors that promote or inhibit growth. The molecules mentioned in this study help to tip the balance toward growth.
Neogenesis Case Study Program
I am delighted to announce my collaboration with the Neogenesis Case Study Program, which presents a unique opportunity to integrate the NeoGenesis Hair Thickening Serum into my trichology protocols. Through these case studies, we aim to spotlight various forms of hair loss experienced by individuals with Black or Brown skin tones.
I aim to shed light on the significant issue of hair loss affecting Black women and provide them with effective solutions. Addressing this often overlooked aspect of hair loss research is essential, particularly concerning women of color.
However, I want to emphasize that participation is open to individuals of all races, and I warmly welcome anyone interested in joining the study as a candidate.
I will conduct the studies with Steve McGee, the President of Neogenesis.
If you are interested in participating in this study, the first step is to schedule a trichology consultation so that I can analyze your scalp and help you identify the cause of your problem.
There are some qualifications to join. Click here to learn more. You will see before-and-after photos and our case study videos showcasing the results.
You can schedule a trichology consultation by completing the New Client Profile Form. Once you have completed it, you will be directed to schedule a consultation on my calendar.
3. Current Limitations and Novel Treatment Approach.
The study acknowledges the limited effectiveness and gender-specific applications of FDA-approved medications like Finasteride and minoxidil, which often have undesirable side effects. However, the research introduces an innovative treatment approach: microneedling and stem cell-released molecules.
These stem-cell-released molecules are formulated in the Neogenesis Hair Thickening Serum. Neogenesis Hair Thickening Serum is formulated with NeoGenesis patented S²RM® technology, a continuation of adult donated stem cells and other botanicals that help reduce shedding, reverse thinning, and normalize the hair growth cycle. This serum helps activate your body's stem cells to heal and repair tissue that makes up hair follicles.
What is microneedling?
Microneedling, also known as collagen induction therapy or derma rolling, is a cosmetic procedure that uses a device containing fine needles to create controlled micro-injuries in the skin.
These micro-injuries stimulate the body's natural wound-healing process, leading to increased collagen and elastin production, essential proteins for maintaining skin structure and elasticity.
During a microneedling procedure, a dermatologist or skincare professional uses a handheld device with small needles to create tiny punctures on the skin's surface. The needles can vary in length, depending on the specific treatment goals and the area of the body being treated.
The needles penetrate the outer layer of the skin, known as the epidermis, and reach the deeper layer, called the dermis.
How can microneedling help with hair loss?
Microneedling can help with hair loss by stimulating the scalp's natural healing response and promoting hair growth.
Microneedling may help reduce inflammation in the scalp, which can be a contributing factor to hair loss. By promoting the release of anti-inflammatory cytokines and reducing pro-inflammatory mediators, microneedling can create a more favorable environment for hair growth.
Microneedling creates micro-channels in the scalp, which can enhance the absorption of topical treatments for hair loss. These treatments can penetrate deeper into the scalp and exert their effects more effectively.
So, using the Neogenesis Hair Thickening Serum in addition to microneedling can be beneficial in reversing hair loss. I recommend seeing a dermatologist for microneedling.
You can use the Neogenesis Hair Thickening Serum without microneedling as well.
Clinical Trial Success.
The heart of the paper lies in a 24-week clinical trial conducted by Dr. Michael Ryan at the Dubai Hair Clinic. Thirteen participants, aged 28 to 64, underwent daily application of stem cell-released molecules combined with bi-weekly microneedling. The results showed that the individual thickness of terminal hair in ten of thirteen patients had significant hair regrowth.
Choosing the Right Stem Cell Types.
The paper underlines the importance of selecting the appropriate stem cell types for therapeutic development. ADSCs take center stage, being touted as safer and more effective than bone marrow mesenchymal stem cells, which have been associated with oncogenic risks.
The research provides a beacon of hope for individuals battling alopecia. The novel combination of micro-needling and stem cell-released molecules derived from the potent ADSCs emerges as a safe, effective treatment for hair regrowth.
This research paves the way for a new era in hair restoration, challenging conventional treatments and bringing forth a promising alternative.